SCHEMBL295452

SCHEMBL295452

C=C(C=CC(=O)O)C(=O)OC1(C(C)C)CC1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.35
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
TSHR P16473 2/20 0.30
TP53 P04637 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30
EGLN3 Q9H6Z9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL295676 0.78
SCHEMBL3952590 0.76 ACHE (0.35) HCAR2TSHR
SCHEMBL674145 0.74 TSHR (0.41) ALDH1A1TSHR
SCHEMBL3899887 0.73 HCAR2 (0.35) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL15355483 0.72 HCAR2 (0.46) HCAR2ALDH1A1GAATSHRTP53
SCHEMBL2360417 0.72 TSHR (0.32) TSHRTP53EGLN1EGLN3
SCHEMBL8106033 0.72 HCAR2 (0.46) HCAR2ALDH1A1GAATSHRTP53
SCHEMBL15355484 0.72 HCAR2 (0.46) HCAR2ALDH1A1GAATSHRTP53
SCHEMBL8106028 0.72 HCAR2 (0.46) HCAR2ALDH1A1GAATSHRTP53
SCHEMBL8092318 0.71 HCAR2 (0.44) HCAR2ALDH1A1GAATSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008042170-A1 COMPOSITION COMPRISING ETHYLENE COPOLYMER E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-04-10 WO claimed
US-20080081861-A1 Composition comprising ethylene copolymer E. I. DU PONT DE NEMOURS AND COMPANY 2008-04-03 US claimed
EP-0084355-B1 ORGANIC ACID CONTAINING FILLED AND PLASTICIZED THERMOPLASTIC COMPOSITIONS BASED ON ETHYLENE INTERPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-07-06 EP claimed
EP-0100066-B1 SURFACTANT-CONTAINING FILLED AND PLASTICIZED THERMOPLASTIC COMPOSITIONS BASED ON ETHYLENE INTERPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-03-12 EP claimed
EP-0045968-B1 FILLED THERMOPLASTIC COMPOSITIONS BASED ON ETHYLENE INTERPOLYMERS AND POLYESTER, POLYETHER AND POLYETHER ESTER PLASTICIZERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-07-17 EP claimed
EP-0045967-B1 FILLED THERMOPLASTIC COMPOSITIONS BASED ON MIXTURES OF ETHYLENE INTERPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-02-13 EP claimed
US-4480061-A Wood-like articles made from cellulosic filler loaded ethylene interpolymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-30 US claimed
US-4472545-A Leather-like articles made from cellulosic filler loaded ethylene interpolymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-09-18 US claimed
EP-0114409-A1 Wood-like articles made from cellulosic filler loaded ethylene interpolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-08-01 EP claimed
EP-0113916-A1 Leather-like articles made from cellulosic filler loaded ethylene interpolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-07-25 EP claimed
US-4434261-A ETHYLENE POLYMER, PLASTICIZER, FILLER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-02-28 US claimed
US-4434258-A AUTOMOTIVE CARPET E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-02-28 US claimed
EP-0101028-A1 Extrudable self-supporting hot melt adhesive sheet E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-02-22 EP claimed
EP-0100066-A1 Surfactant-containing filled and plasticized thermoplastic compositions based on ethylene interpolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-02-08 EP claimed
US-4430468-A SOUND DEADENING COATINGS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-02-07 US claimed
US-4403007-A POLYMER BLENDS, ACOUSTICAL DAMPENING E. I. DU PONT DE NEMOURS & CO. (US) 1983-09-06 US claimed
EP-0084355-A1 Organic acid containing filled and plasticized thermoplastic compositions based on ethylene interpolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-27 EP claimed
US-4379190-A Filled thermoplastic compositions based on mixtures of ethylene interpolymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-04-05 US claimed
EP-0045967-A2 Filled thermoplastic compositions based on mixtures of ethylene interpolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-02-17 EP claimed
EP-0045968-A2 Filled thermoplastic compositions based on ethylene interpolymers and polyester, polyether and polyether ester plasticizers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-02-17 EP claimed