Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 8/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.39 |
| ▸ | ESR1 | P03372 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24362670 | 0.90 | MAPK14 (0.44) | PTGER1MAPK14ALDH1A1RORC | |
| SCHEMBL29545551 | 0.90 | MAPK14 (0.44) | PTGER1MAPK14ALDH1A1RORC | |
| SCHEMBL29545802 | 0.82 | PTGS2 (0.41) | MAPK14ALDH1A1ESR1RORC | |
| SCHEMBL24357559 | 0.82 | PTGS2 (0.41) | MAPK14ALDH1A1ESR1RORC | |
| SCHEMBL30596785 | 0.77 | PTGS2 (0.37) | PTGER1 | |
| SCHEMBL31249054 | 0.76 | SRD5A2 (0.53) | SRD5A1SRD5A2ESR1 | |
| SCHEMBL12074171 | 0.74 | MAPK14 (0.40) | MAPK14ALDH1A1ESR1 | |
| SCHEMBL24362672 | 0.73 | MAPK14 (0.43) | PTGER1MAPK14ALDH1A1 | |
| SCHEMBL23528104 | 0.73 | PTGS2 (0.39) | MAPK14ALDH1A1SRD5A1SRD5A2ESR1 | |
| SCHEMBL29545398 | 0.73 | PTGS2 (0.39) | MAPK14ALDH1A1SRD5A1SRD5A2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4508032-A1 | NOVEL SUBSTITUTED FLUORINATED VINYL-N-PROPYL-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | Sanofi (FR) | 2025-02-19 | — | — | EP | disclosed |
| WO-2023198905-A1 | NOVEL SUBSTITUTED FLUORINATED VINYL-N-PROPYL-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2023-10-19 | — | — | WO | disclosed |
| EP-4228757-A1 | SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS AND THEIR DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | Sanofi (FR) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022084298-A1 | SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS AND THEIR DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2022-04-28 | — | — | WO | disclosed |