Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | BRD1 | O95696 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.42 |
| ▸ | WNT3A | P56704 | 6/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
| ▸ | PIR | O00625 | 1/20 | 0.39 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23432653 | 1.00 | TRIM24 (0.44) | TRIM24BRD1BRPF1DYRK1ADYRK1B | |
| SCHEMBL317647 | 0.89 | PKLR (0.48) | DYRK1ADYRK1BQPCTPRKCIPKLR | |
| Hydrochloric Acid SCHEMBL507190 | 0.87 | PKLR (0.47) | DYRK1ADYRK1BQPCTPRKCIPKLR | |
| SCHEMBL13760630 | 0.86 | QPCT (0.42) | TRIM24BRD1BRPF1CTNNB1WNT3A | |
| SCHEMBL24783881 | 0.83 | TRIM24 (0.43) | TRIM24BRD1BRPF1DYRK1ADYRK1B | |
| SCHEMBL16670328 | 0.81 | CTNNB1 (0.43) | TRIM24BRD1BRPF1DYRK1ADYRK1B | |
| SCHEMBL12196111 | 0.79 | CYP1A2 (0.51) | MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2245406 | 0.79 | CYP1A2 (0.65) | CTNNB1WNT3AQPCTPIRHSF1 | |
| SCHEMBL29739444 | 0.79 | CYP1A2 (0.65) | CTNNB1WNT3AQPCTPIRHSF1 | |
| SCHEMBL18175882 | 0.79 | TRIM24 (0.54) | TRIM24BRD1BRPF1DYRK1ADYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214231-B | 5HT2A receptor antagonists and their medical uses | 瀚远医药有限公司 | 2022-04-08 | — | — | CN | disclosed |