Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 12/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.38 |
| ▸ | ACACB | O00763 | 4/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27098055 | 1.00 | PIK3CD (0.38) | PIK3CDPIK3CAPIK3CBPIK3CGACACB | |
| SCHEMBL27136221 | 1.00 | PIK3CD (0.38) | PIK3CDPIK3CAPIK3CBPIK3CGACACB | |
| SCHEMBL27098057 | 0.85 | PIK3CD (0.34) | PIK3CDPIK3CAPIK3CBPIK3CGACACB | |
| SCHEMBL27139547 | 0.85 | ACACB (0.39) | PIK3CDPIK3CAPIK3CBPIK3CGACACB | |
| SCHEMBL29547656 | 0.85 | ACACB (0.39) | PIK3CDPIK3CAPIK3CBPIK3CGACACB | |
| SCHEMBL27098053 | 0.85 | ACACB (0.39) | PIK3CDPIK3CAPIK3CBPIK3CGACACB | |
| SCHEMBL20129074 | 0.83 | GRIN2B (0.35) | PIK3CDPIK3CAPIK3CBPIK3CGKCNH2 | |
| SCHEMBL20120826 | 0.82 | TDO2 (0.38) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL20120825 | 0.82 | TDO2 (0.38) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL29547432 | 0.82 | TDO2 (0.38) | PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954801-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114867727-B | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-114867727-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| EP-3999182-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |