Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 18/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19641810 | 1.00 | NOTUM (0.50) | NOTUMTTR | |
| SCHEMBL19662117 | 0.89 | NOTUM (0.56) | NOTUMTTR | |
| SCHEMBL19662652 | 0.89 | NOTUM (0.56) | NOTUMTTR | |
| SCHEMBL29548036 | 0.89 | NOTUM (0.56) | NOTUMTTR | |
| SCHEMBL19642435 | 0.89 | NOTUM (0.56) | NOTUMTTR | |
| SCHEMBL19642429 | 0.88 | HSD11B1 (0.40) | NOTUMTTR | |
| SCHEMBL29547630 | 0.88 | HSD11B1 (0.40) | NOTUMTTR | |
| SCHEMBL19642423 | 0.88 | NOTUM (0.49) | NOTUMTTR | |
| SCHEMBL29547637 | 0.88 | NOTUM (0.49) | NOTUMTTR | |
| SCHEMBL19642375 | 0.87 | NOTUM (0.55) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311860-B | Xanthone derivatives for the treatment or prevention of hepatitis B virus diseases | 豪夫迈·罗氏有限公司 | 2022-04-08 | — | — | CN | claimed |
| CN-109311860-B | Xanthone derivatives for the treatment or prevention of hepatitis B virus diseases | 豪夫迈·罗氏有限公司 | 2022-04-08 | — | — | CN | disclosed |