Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20120835 | 1.00 | METAP2 (0.43) | METAP2ROCK2 | |
| SCHEMBL20128905 | 0.87 | METAP2 (0.40) | METAP2ROCK2 | |
| SCHEMBL20120312 | 0.86 | METAP2 (0.44) | METAP2 | |
| SCHEMBL29547965 | 0.84 | METAP2 (0.38) | METAP2ROCK2 | |
| SCHEMBL20120739 | 0.84 | METAP2 (0.38) | METAP2ROCK2 | |
| SCHEMBL20128570 | 0.84 | METAP2 (0.47) | METAP2ROCK2 | |
| SCHEMBL20128580 | 0.83 | METAP2 (0.48) | METAP2 | |
| SCHEMBL22906719 | 0.81 | METAP2 (0.47) | METAP2 | |
| SCHEMBL20128560 | 0.80 | METAP2 (0.49) | METAP2ROCK2 | |
| SCHEMBL20128988 | 0.79 | METAP2 (0.40) | METAP2ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3999182-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |