Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 6/20 | 0.32 |
| ▸ | ACACA | Q13085 | 3/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27138595 | 1.00 | DGAT1 (0.33) | DGAT1ACACBACACAFFAR1 | |
| SCHEMBL27097991 | 1.00 | DGAT1 (0.33) | DGAT1ACACBACACAFFAR1 | |
| SCHEMBL29773877 | 0.85 | ACACB (0.32) | DGAT1ACACBACACA | |
| SCHEMBL27097985 | 0.85 | DGAT1 (0.36) | DGAT1ACACBACACAFFAR1 | |
| SCHEMBL29773880 | 0.85 | DGAT1 (0.36) | DGAT1ACACBACACAFFAR1 | |
| SCHEMBL27139155 | 0.84 | TSHR (0.33) | DGAT1ACACBACACA | |
| SCHEMBL27097982 | 0.84 | TSHR (0.33) | DGAT1ACACBACACA | |
| SCHEMBL29547446 | 0.84 | TSHR (0.33) | DGAT1ACACBACACA | |
| SCHEMBL20233663 | 0.84 | ACACB (0.31) | ACACBACACAFFAR1 | |
| SCHEMBL30230062 | 0.84 | GRIN1 (0.31) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954801-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114867727-B | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-114867727-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| EP-3999182-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |