Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 11/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22906862 | 1.00 | BRD9 (0.41) | BRD9CRBNDDB1MAPTALDH1A1 | |
| SCHEMBL27147337 | 0.93 | CRBN (0.39) | BRD9CRBNDDB1MAPTALDH1A1 | |
| SCHEMBL22907287 | 0.86 | CRBN (0.41) | BRD9CRBNDDB1ALDH1A1CHRM2 | |
| SCHEMBL20372689 | 0.85 | CRBN (0.43) | BRD9CRBNDDB1MAPTALDH1A1 | |
| SCHEMBL20120416 | 0.82 | CRBN (0.55) | CRBNDDB1MAPTALDH1A1CHRM2 | |
| SCHEMBL27098129 | 0.81 | CRBN (0.41) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL25546133 | 0.80 | TNF (0.44) | BRD9MAPTALDH1A1TDP1IRAK4 | |
| SCHEMBL25698575 | 0.80 | CRBN (0.43) | BRD9CRBNDDB1MAPTALDH1A1 | |
| SCHEMBL21896543 | 0.80 | CRBN (0.46) | BRD9CRBNDDB1ALDH1A1CHRM2 | |
| SCHEMBL29548034 | 0.79 | CRBN (0.61) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954801-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114867727-B | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-114867727-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| EP-3999182-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |