Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.57 |
| ▸ | AHR | P35869 | 5/20 | 0.46 |
| ▸ | MAOA | P21397 | 6/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19641739 | 1.00 | TTR (0.57) | TTRAHRMAOAACELMNA | |
| SCHEMBL19642367 | 0.87 | TTR (0.53) | TTRAHRMAOAACELMNA | |
| SCHEMBL21130060 | 0.87 | TTR (0.53) | TTRAHRMAOAACELMNA | |
| SCHEMBL19642446 | 0.87 | TTR (0.44) | TTRAHRMAOAACELMNA | |
| SCHEMBL19642257 | 0.82 | TTR (0.64) | TTRAHRMAOALMNAKDM4E | |
| SCHEMBL24410070 | 0.80 | TTR (0.62) | TTRAHRMAOALMNAKDM4E | |
| SCHEMBL20317229 | 0.80 | TTR (0.58) | TTRAHRMAOALMNAKDM4E | |
| SCHEMBL21129776 | 0.78 | TTR (0.53) | TTRAHRMAOALMNAKDM4E | |
| SCHEMBL8815383 | 0.78 | TTR (0.65) | TTRAHRMAOALMNAKDM4E | |
| SCHEMBL31193433 | 0.77 | MAOA (0.64) | TTRAHRMAOALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311860-B | Xanthone derivatives for the treatment or prevention of hepatitis B virus diseases | 豪夫迈·罗氏有限公司 | 2022-04-08 | — | — | CN | disclosed |