SCHEMBL29548286 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	GBA1	P04062	1/20	0.44

▸	MBOAT4	Q96T53	1/20	0.38

▸	RAB9A	P51151	4/20	0.36

▸	NOS1	P29475	1/20	0.35

▸	NPC1	O15118	2/20	0.34

▸	KDM4E	B2RXH2	2/20	0.34

▸	ATM	Q13315	1/20	0.34

▸	BRD4	O60885	1/20	0.34

▸	MITF	O75030	1/20	0.34

▸	L3MBTL1	Q9Y468	1/20	0.34

▸	GRM2	Q14416	1/20	0.33

▸	HPGD	P15428	1/20	0.33

▸	MCHR1	Q99705	2/20	0.32

▸	MAPT	P10636	1/20	0.32

▸	ALDH1A1	P00352	1/20	0.32

▸	TP53	P04637	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL1816193	0.85	GBA1 (0.47)	GBA1MBOAT4RAB9ANPC1KDM4E
SCHEMBL2147686	0.84	GBA1 (0.40)	GBA1MBOAT4RAB9ANPC1KDM4E
SCHEMBL6478582	0.83	GBA1 (0.39)	GBA1MBOAT4RAB9ANPC1KDM4E
SCHEMBL14659458	0.82	GBA1 (0.37)	GBA1MBOAT4RAB9ANPC1KDM4E
SCHEMBL4764131	0.81	GBA1 (0.41)	GBA1MBOAT4RAB9ANPC1L3MBTL1
SCHEMBL21911797	0.81	GBA1 (0.41)	GBA1KDM4EMCHR1ALDH1A1
SCHEMBL30189191	0.81	GBA1 (0.41)	GBA1KDM4EMCHR1ALDH1A1
SCHEMBL10263917	0.80	SYK (0.40)	RAB9ANOS1NPC1KDM4EBRD4
SCHEMBL1855342	0.77	GBA1 (0.46)	GBA1MBOAT4RAB9ANPC1KDM4E
SCHEMBL14658492	0.77	DUT (0.39)	GBA1MBOAT4KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022070288-A1	NITROGEN-CONTAINING BICYCLIC COMPOUND	旭化成ファーマ株式会社	2022-04-07	—	—	WO	disclosed