Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 9/20 | 0.35 |
| ▸ | ATR | Q13535 | 6/20 | 0.35 |
| ▸ | MTOR | P42345 | 8/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.32 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27149004 | 1.00 | TDO2 (0.36) | TDO2ATMATRMTORPIK3CA | |
| SCHEMBL27098363 | 1.00 | TDO2 (0.36) | TDO2ATMATRMTORPIK3CA | |
| SCHEMBL29547248 | 0.91 | TDO2 (0.41) | TDO2ATMATRMTORPIK3CA | |
| SCHEMBL20120391 | 0.91 | TDO2 (0.41) | TDO2ATMATRMTORPIK3CA | |
| SCHEMBL20128928 | 0.91 | TDO2 (0.41) | TDO2ATMATRMTORPIK3CA | |
| SCHEMBL29547284 | 0.91 | TDO2 (0.41) | TDO2ATMATRMTORPIK3CA | |
| Hydrochloric Acid SCHEMBL29547386 | 0.90 | TDO2 (0.41) | TDO2ATMATRMTORPIK3CA | |
| Hydrochloric Acid SCHEMBL27146420 | 0.90 | TDO2 (0.41) | TDO2ATMATRMTORPIK3CA | |
| Hydrochloric Acid SCHEMBL27146421 | 0.90 | TDO2 (0.41) | TDO2ATMATRMTORPIK3CA | |
| SCHEMBL27098360 | 0.89 | ATM (0.37) | TDO2ATMATRMTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954801-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114867727-B | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-114867727-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| EP-3999182-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |