Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 6/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28496413 | 1.00 | L3MBTL1 (0.50) | L3MBTL1POLBEPAS1TRPA1SLC6A2 | |
| SCHEMBL16047925 | 0.91 | EPAS1 (0.50) | L3MBTL1EPAS1TRPA1SLC6A2SLC6A4 | |
| SCHEMBL16738742 | 0.86 | EPAS1 (0.51) | L3MBTL1EPAS1TRPA1ALDH1A1HSPB1 | |
| SCHEMBL30194335 | 0.86 | EPAS1 (0.51) | L3MBTL1EPAS1TRPA1ALDH1A1HSPB1 | |
| SCHEMBL2443815 | 0.85 | EPAS1 (0.48) | EPAS1TRPA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16047284 | 0.84 | EPAS1 (0.50) | L3MBTL1EPAS1TRPA1ALDH1A1HSPB1 | |
| SCHEMBL16048593 | 0.83 | EPAS1 (0.48) | EPAS1TRPA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16069092 | 0.79 | POLB (0.46) | L3MBTL1POLBEPAS1TRPA1SLC6A2 | |
| SCHEMBL15067206 | 0.79 | KDM4E (0.48) | EPAS1ALDH1A1GAA | |
| SCHEMBL20155521 | 0.77 | EPAS1 (0.44) | EPAS1TRPA1ALDH1A1HSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041253-B | Pyridine N-oxide derivative and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-03-29 | — | — | CN | disclosed |