Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 12/20 | 0.76 |
| ▸ | SRC | P12931 | 14/20 | 0.75 |
| ▸ | FGFR1 | P11362 | 10/20 | 0.75 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.75 |
| ▸ | HCK | P08631 | 1/20 | 0.61 |
| ▸ | FLT3 | P36888 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22807435 | 1.00 | MAP3K7 (0.76) | MAP3K7SRCFGFR1MAP2K1MAPK1 | |
| SCHEMBL22828520 | 0.86 | SRC (1.00) | MAP3K7SRCFGFR1MAP2K1MAPK1 | |
| SCHEMBL31684786 | 0.86 | SRC (1.00) | MAP3K7SRCFGFR1MAP2K1MAPK1 | |
| SCHEMBL22807484 | 0.82 | SRC (0.70) | MAP3K7SRCFGFR1MAP2K1MAPK1 | |
| SCHEMBL22807490 | 0.82 | SRC (0.83) | MAP3K7SRCFGFR1MAP2K1MAPK1 | |
| SCHEMBL18018944 | 0.82 | SRC (0.69) | MAP3K7SRCFGFR1MAP2K1MAPK1 | |
| SCHEMBL22807431 | 0.82 | SRC (0.69) | MAP3K7SRCFGFR1MAP2K1MAPK1 | |
| SCHEMBL22807493 | 0.81 | SRC (0.82) | MAP3K7SRCFGFR1MAP2K1MAPK1 | |
| SCHEMBL22807377 | 0.81 | SRC (0.82) | MAP3K7SRCFGFR1MAP2K1MAPK1 | |
| SCHEMBL28980984 | 0.81 | SRC (0.82) | MAP3K7SRCFGFR1MAP2K1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986411-A1 | SMALL MOLECULE INHIBITORS OF SRC TYROSINE KINASE | Dana-Farber Cancer Institute, Inc. (US) | 2022-04-27 | — | — | EP | disclosed |