Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 17/20 | 0.48 |
| ▸ | CALCA | P06881 | 3/20 | 0.47 |
| ▸ | RAMP1 | O60894 | 11/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16658950 | 1.00 | CALCRL (0.48) | CALCRLCALCARAMP1 | |
| SCHEMBL10246001 | 0.89 | CALCRL (0.51) | CALCRLCALCARAMP1 | |
| SCHEMBL10207148 | 0.85 | CALCA (0.46) | CALCRLCALCARAMP1 | |
| SCHEMBL837966 | 0.85 | CALCA (0.46) | CALCRLCALCARAMP1 | |
| SCHEMBL31126001 | 0.83 | CALCRL (0.50) | CALCRLCALCARAMP1 | |
| SCHEMBL838209 | 0.83 | CALCRL (0.50) | CALCRLRAMP1 | |
| SCHEMBL977185 | 0.83 | CALCRL (0.50) | CALCRLRAMP1 | |
| SCHEMBL22110811 | 0.83 | CALCRL (0.51) | CALCRLRAMP1 | |
| SCHEMBL31039442 | 0.83 | CALCRL (0.50) | CALCRLRAMP1 | |
| SCHEMBL976476 | 0.83 | CALCRL (0.50) | CALCRLCALCARAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114245798-B | CGRP antagonist compounds | 奈克斯拉制药英国有限公司 | 2024-08-27 | — | — | CN | disclosed |
| EP-3983416-A1 | CGRP ANTAGONIST COMPOUNDS | Heptares Therapeutics Limited (GB) | 2022-04-20 | — | — | EP | disclosed |