Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30397603 | 0.72 | TBK1 (0.40) | TBK1 | |
| SCHEMBL29512208 | 0.71 | USP8 (0.40) | — | |
| Hydrochloric Acid SCHEMBL30209394 | 0.69 | USP8 (0.39) | — | |
| SCHEMBL23529936 | 0.66 | ALK (0.33) | — | |
| SCHEMBL29549997 | 0.66 | ALK (0.33) | — | |
| SCHEMBL16460460 | 0.65 | GRM5 (0.34) | — | |
| SCHEMBL13082294 | 0.64 | — | — | |
| SCHEMBL23761231 | 0.64 | TBK1 (0.48) | TBK1 | |
| SCHEMBL23753850 | 0.62 | TBK1 (0.40) | TBK1 | |
| SCHEMBL22717508 | 0.62 | SLC6A4 (0.38) | TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114302886-B | Triazolopyridazine derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-114302886-A | Triazolopyridazine derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2022-04-08 | — | — | CN | disclosed |