SCHEMBL29550511

SCHEMBL29550511

O=C(O)c1cccc2ncccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 1/20 0.60
ACLY P53396 1/20 0.58
KDM4E B2RXH2 6/20 0.57
TDP1 Q9NUW8 1/20 0.57
L3MBTL1 Q9Y468 3/20 0.55
MAPT P10636 3/20 0.55
ALDH1A1 P00352 3/20 0.55
CYP3A4 P08684 1/20 0.55
ALOX15 P16050 1/20 0.55
TSHR P16473 1/20 0.55
BLM P54132 1/20 0.55
AGER Q15109 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
KDM4A O75164 2/20 0.54
EGLN1 Q9GZT9 2/20 0.54
KDM6B O15054 1/20 0.54
KDM6A O15550 1/20 0.54
TET3 O43151 1/20 0.54
KDM4B O94953 1/20 0.54
KDM5C P41229 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL335469 1.00 NSD2 (0.60) NSD2ACLYKDM4ETDP1L3MBTL1
SCHEMBL28727190 0.98 NSD2 (0.59) NSD2ACLYKDM4ETDP1L3MBTL1
SCHEMBL5680479 0.98 NSD2 (0.59) NSD2ACLYKDM4ETDP1L3MBTL1
Hydrochloric Acid SCHEMBL5450942 0.98 NSD2 (0.59) NSD2ACLYKDM4ETDP1L3MBTL1
SCHEMBL5680469 0.98 NSD2 (0.59) NSD2ACLYKDM4ETDP1L3MBTL1
Formaldehyde SCHEMBL27690889 0.96 NSD2 (0.57) NSD2ACLYKDM4ETDP1L3MBTL1
Acetic Acid SCHEMBL27656229 0.95 NSD2 (0.56) NSD2ACLYKDM4ETDP1L3MBTL1
Aziridine SCHEMBL27648195 0.92 NSD2 (0.54) NSD2ACLYKDM4ETDP1L3MBTL1
Alcohol SCHEMBL28316967 0.92 NSD2 (0.57) NSD2ACLYKDM4ETDP1L3MBTL1
Quinoline SCHEMBL27803388 0.92 NR4A1 (0.58) NSD2ACLYKDM4ETDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119556538-A Alkaline stripping liquid for silicon-based surface composite film and stripping method thereof 湖北兴福电子材料股份有限公司 2025-03-04 CN claimed
EP-4340989-A1 METHOD OF MANUFACTURE AND SCALE-UP OF THE METAL-ORGANIC FRAMEWORK CU(QC)2 ExxonMobil Technology and Engineering Company (US) 2024-03-27 EP claimed
WO-2022246150-A1 METHOD OF MANUFACTURE AND SCALE-UP OF THE METAL-ORGANIC FRAMEWORK CU(QC)2 ExxonMobil Technology and Engineering Company (US) 2022-11-24 WO claimed
CN-119661553-A Brucea javanica kurol quinoline derivative and preparation method and application thereof 中国人民解放军西部战区总医院 2025-03-21 CN disclosed
CN-119556538-A Alkaline stripping liquid for silicon-based surface composite film and stripping method thereof 湖北兴福电子材料股份有限公司 2025-03-04 CN disclosed
EP-4340989-A1 METHOD OF MANUFACTURE AND SCALE-UP OF THE METAL-ORGANIC FRAMEWORK CU(QC)2 ExxonMobil Technology and Engineering Company (US) 2024-03-27 EP disclosed
WO-2024026423-A1 SUBSTITUTED QUINOLINE DERIVATIVES AS PI3K INHIBITORS BLACK DIAMOND THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
US-20230203058-A1 MACROCYCLIC DIAMINE DERIVATIVES AS ENT INHIBITORS FOR THE TREATMENT OF CANCERS, AND COMBINATION THEREOF WITH ADENOSINE RECEPTOR ANTAGONISTS iTeos Belgium SA (BE) 2023-06-29 US disclosed
EP-4097101-A1 1H-PYRAZOLO[4,3-D]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS Bristol-Myers Squibb Company (US) 2022-12-07 EP disclosed
WO-2022246150-A1 METHOD OF MANUFACTURE AND SCALE-UP OF THE METAL-ORGANIC FRAMEWORK CU(QC)2 ExxonMobil Technology and Engineering Company (US) 2022-11-24 WO disclosed
EP-4055014-A1 PYRROLIDINE AND PIPERIDINE COMPOUNDS Yuhan Corporation (KR) 2022-09-14 EP disclosed
EP-4021406-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS Delpor, Inc. (US) 2022-07-06 EP disclosed
WO-2022063303-A1 A CLASS OF FUSED RING COMPOUNDS, AND PREPARATION AND USE THEREOF 石药集团中奇制药技术(石家庄)有限公司 2022-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203058-A1 MACROCYCLIC DIAMINE DERIVATIVES AS ENT INHIBITORS FOR THE TREATMENT OF CANCERS, AND COMBINATION THEREOF WITH ADENOSINE RECEPTOR ANTAGONISTS ENTPD1, SLC29A1, ENTPD5 NSD2 2023/4885ACLY 1505/4885KDM4E 2852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.