Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.59 |
| ▸ | ACLY | P53396 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | AGER | Q15109 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KDM4A | O75164 | 2/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.53 |
| ▸ | KDM6B | O15054 | 1/20 | 0.53 |
| ▸ | KDM6A | O15550 | 1/20 | 0.53 |
| ▸ | TET3 | O43151 | 1/20 | 0.53 |
| ▸ | KDM4B | O94953 | 1/20 | 0.53 |
| ▸ | KDM5C | P41229 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29550511 | 0.98 | NSD2 (0.60) | NSD2ACLYKDM4ETDP1L3MBTL1 | |
| SCHEMBL335469 | 0.98 | NSD2 (0.60) | NSD2ACLYKDM4ETDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5450942 | 0.96 | NSD2 (0.59) | NSD2ACLYKDM4ETDP1L3MBTL1 | |
| SCHEMBL5680479 | 0.96 | NSD2 (0.59) | NSD2ACLYKDM4ETDP1L3MBTL1 | |
| SCHEMBL28727190 | 0.96 | NSD2 (0.59) | NSD2ACLYKDM4ETDP1L3MBTL1 | |
| Formaldehyde SCHEMBL27690889 | 0.95 | NSD2 (0.57) | NSD2ACLYKDM4ETDP1L3MBTL1 | |
| Acetic Acid SCHEMBL27656229 | 0.93 | NSD2 (0.56) | NSD2ACLYKDM4ETDP1L3MBTL1 | |
| Alcohol SCHEMBL28316967 | 0.90 | NSD2 (0.57) | NSD2ACLYKDM4ETDP1L3MBTL1 | |
| Aziridine SCHEMBL27648195 | 0.90 | NSD2 (0.54) | NSD2ACLYKDM4ETDP1L3MBTL1 | |
| Quinoline SCHEMBL27803388 | 0.90 | NR4A1 (0.58) | NSD2ACLYKDM4ETDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628989-B1 | NOVEL 14 AND 15 MEMBERED-RING COMPOUNDS | GLAXO GROUP LTD (GB) | 2006-12-20 | — | — | EP | disclosed |
| EP-1628989-A1 | NOVEL 14 AND 15 MEMBERED-RING COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004101587-A1 | NOVEL 14 AND 15 MEMBERRED-RING COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-11-25 | — | — | WO | disclosed |