Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20586356 | 1.00 | KDM6B (0.56) | KDM6BPPARGPPARAPTPRBPTPRA | |
| SCHEMBL18248036 | 1.00 | KDM6B (0.56) | KDM6BPPARGPPARAPTPRBPTPRA | |
| SCHEMBL17336531 | 0.86 | LDHA (0.47) | KDM6BPPARGPPARAPTPRBKDM4E | |
| SCHEMBL2166889 | 0.84 | KDM6B (0.61) | KDM6BPPARAPTPRAKDM4EUSP2 | |
| SCHEMBL7230282 | 0.84 | KDM6B (0.61) | KDM6BPPARGPPARAPTPRA | |
| SCHEMBL7711037 | 0.84 | KDM6B (0.61) | KDM6BPPARGPPARAPTPRA | |
| SCHEMBL2166894 | 0.84 | KDM6B (0.61) | KDM6BPPARAPTPRAKDM4EUSP2 | |
| SCHEMBL27410905 | 0.84 | KDM6B (0.38) | KDM6BPPARGPPARAPTPRBPTGS1 | |
| SCHEMBL29552177 | 0.82 | SLC7A5 (0.57) | KDM4EUSP2EGFRLCKFYN | |
| SCHEMBL18248167 | 0.82 | SLC7A5 (0.57) | KDM4EUSP2EGFRLCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114891070-A | Anthelmintic depsipeptide compounds | 勃林格殷格翰动物保健美国公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-107835818-B | Anthelmintic depsipeptide compounds | 勃林格殷格翰动物保健美国公司 | 2022-04-29 | — | — | CN | disclosed |