Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | KIF5B | P33176 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | ABL2 | P42684 | 2/20 | 0.41 |
| ▸ | ITK | Q08881 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 5/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 8/20 | 0.39 |
| ▸ | BTK | Q06187 | 3/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24458957 | 0.95 | SRC (0.46) | SRCRETKIF5BEGFRABL1 | |
| SCHEMBL24458531 | 0.95 | RET (0.45) | RETKIF5BITKFGFR1FGFR4 | |
| SCHEMBL31523837 | 0.95 | RET (0.45) | RETKIF5BITKFGFR1FGFR4 | |
| SCHEMBL24458503 | 0.95 | RET (0.45) | RETKIF5BITKFGFR1FGFR4 | |
| SCHEMBL24458900 | 0.90 | RET (0.46) | RETKIF5BITKFGFR1FGFR4 | |
| SCHEMBL24458867 | 0.89 | ITK (0.51) | ITKFGFR1FGFR4FGFR2BTK | |
| SCHEMBL24458598 | 0.88 | ITK (0.46) | RETKIF5BEGFRITKFGFR1 | |
| SCHEMBL24458458 | 0.88 | FGFR4 (0.46) | EGFRITKFGFR1FGFR4FGFR2 | |
| SCHEMBL31523724 | 0.88 | FGFR4 (0.46) | EGFRITKFGFR1FGFR4FGFR2 | |
| SCHEMBL31523780 | 0.87 | ITK (0.44) | RETKIF5BEGFRITKFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247816-A1 | SRC INHIBITORS AND USES THEREOF | Relay Therapeutics, Inc. (US) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022109551-A1 | SRC INHIBITORS AND USES THEREOF | RELAY THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |