Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23688590 | 1.00 | CA1 (0.40) | CA1CA2CA4KMT2AMAPT | |
| SCHEMBL19302210 | 1.00 | CA1 (0.40) | CA1CA2CA4KMT2AMAPT | |
| SCHEMBL23688592 | 1.00 | CA1 (0.40) | CA1CA2CA4KMT2AMAPT | |
| SCHEMBL23688589 | 1.00 | CA1 (0.40) | CA1CA2CA4KMT2AMAPT | |
| SCHEMBL19285608 | 1.00 | CA1 (0.40) | CA1CA2CA4KMT2AMAPT | |
| SCHEMBL19565871 | 0.87 | — | — | |
| SCHEMBL19548872 | 0.87 | — | — | |
| SCHEMBL22957070 | 0.87 | — | — | |
| SCHEMBL2068500 | 0.75 | MAPT (0.39) | CA1CA2CA4KMT2AMAPT | |
| SCHEMBL9501225 | 0.75 | KMT2A (0.44) | CA1CA2CA4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11306107-B2 | Compounds that inhibit MCL-1 protein | AMGEN INC. (US) | 2022-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11306107-B2 | Compounds that inhibit MCL-1 protein | MCL1, BCL9, BCL2L1 | CA1 4607/4885CA2 4701/4885CA4 4869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.