Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | CTRC | Q99895 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20969924 | 0.81 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL20969209 | 0.81 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL9541433 | 0.79 | MEN1 (0.45) | KMT2AMEN1ALDH1A1CYP19A1PRSS1 | |
| SCHEMBL22772431 | 0.76 | CA1 (0.41) | KMT2ACA1CA2CA4NOS3 | |
| SCHEMBL18611288 | 0.76 | CA1 (0.41) | KMT2ACA1CA2CA4NOS3 | |
| SCHEMBL3594380 | 0.75 | AKR1C4 (0.41) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL10406320 | 0.75 | MEN1 (0.42) | KMT2AMEN1ALDH1A1CYP19A1PRSS1 | |
| SCHEMBL10406318 | 0.75 | MEN1 (0.42) | KMT2AMEN1ALDH1A1CYP19A1PRSS1 | |
| SCHEMBL10406322 | 0.75 | MEN1 (0.42) | KMT2AMEN1ALDH1A1CYP19A1PRSS1 | |
| SCHEMBL23688589 | 0.75 | CA1 (0.40) | KMT2ACA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250696-A | Treatment of degenerative diseases | STERLING WINTHROP INC. (US) | 1993-10-05 | — | — | US | disclosed |