SCHEMBL29554395

SCHEMBL29554395

C[C@@H](O)[C@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)C(C)(C)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)O

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 20/20 0.63
▸ SCTR P47872 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29663731 0.97 GLP1R (0.66) GLP1RSCTR
SCHEMBL30978208 0.96 GLP1R (0.65) GLP1RSCTR
SCHEMBL30278876 0.95 GLP1R (0.60) GLP1RSCTR
SCHEMBL31058454 0.95 GLP1R (0.71) GLP1RSCTR
SCHEMBL31058452 0.95 GLP1R (0.71) GLP1RSCTR
SCHEMBL30320200 0.94 GLP1R (0.56) GLP1RSCTR
SCHEMBL30207768 0.94 GLP1R (0.56) GLP1RSCTR
SCHEMBL30320225 0.94 GLP1R (0.56) GLP1RSCTR
SCHEMBL30320221 0.94 GLP1R (0.56) GLP1RSCTR
SCHEMBL29913342 0.94 GLP1R (0.56) GLP1RSCTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115073582-B Polypeptide compound and application thereof in preventing or treating diabetes or diabetic complications 深圳市图微安创科技开发有限公司 2024-12-20 — — CN claimed
CN-112791178-B GLP-1R/GCGR dual agonist polypeptide derivatives for preventing or treating renal fibrosis 深圳市图微安创科技开发有限公司 2024-10-29 — — CN claimed
CN-114585640-B GLP-1R/GCGR double-target agonist polypeptide derivative for treating liver fibrosis related to viral hepatitis 深圳市图微安创科技开发有限公司 2024-06-14 — — CN claimed
CN-114945589-B Polypeptide compound and application thereof in preventing or treating diabetes or diabetic complications 深圳市图微安创科技开发有限公司 2024-05-24 — — CN claimed
CN-112898405-B Polypeptide compound and application thereof in preventing or treating diabetes or diabetic complications 深圳市图微安创科技开发有限公司 2023-02-28 — — CN claimed
CN-106046145-B GLP-1R/GCGR dual-target agonist polypeptides for treating fatty liver disease, hyperlipidemia and arteriosclerosis 深圳市图微安创科技开发有限公司 2022-11-04 — — CN claimed
CN-115181175-A GLP-1R/GCGR dual-target agonist polypeptides for treating fatty liver disease, hyperlipidemia and arteriosclerosis 深圳市图微安创科技开发有限公司 2022-10-14 — — CN claimed
EP-4724472-A2 GLP-1/GIP DUAL, GLP-1/GCG DUAL AND GLP-1/GIP/GCG TRIPLE RECEPTOR AGONISTS Sun Pharmaceutical Industries Limited (IN) 2026-04-15 — — EP disclosed
CN-115073582-B Polypeptide compound and application thereof in preventing or treating diabetes or diabetic complications 深圳市图微安创科技开发有限公司 2024-12-20 — — CN disclosed
WO-2024252367-A2 NOVEL GLP-1/GIP DUAL AND GLP-1/GCG DUAL RECEPTOR AGONISTS SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2024-12-12 — — WO disclosed
CN-112791178-B GLP-1R/GCGR dual agonist polypeptide derivatives for preventing or treating renal fibrosis 深圳市图微安创科技开发有限公司 2024-10-29 — — CN disclosed
CN-114585640-B GLP-1R/GCGR double-target agonist polypeptide derivative for treating liver fibrosis related to viral hepatitis 深圳市图微安创科技开发有限公司 2024-06-14 — — CN disclosed
US-20240174728-A1 A USE OF A POLYPEPTIDE COMPOUND IN THE PREPARATION OF DRUGS FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASES AND RELATED INTESTINAL FIBROSIS SHENZHEN TURIER BIOTECH CO., LTD. (CN) 2024-05-30 — — US disclosed
CN-114945589-A Polypeptide compound and application thereof in preventing or treating diabetes or diabetic complications 深圳市图微安创科技开发有限公司 2022-08-26 — — CN disclosed
US-11419918-B2 Treatment of biliary cirrhosis based on oxyntomodulin analogue GLP-1R/GCGR dual-target agonist peptide SHENZHEN TURIER BIOTECH CO., LTD. 2022-08-23 — — US disclosed
CN-114920818-A Treatment of biliary cirrhosis based on oxyntomodulin analog GLP-1R/GCGR dual-target agonist polypeptide 深圳市图微安创科技开发有限公司 2022-08-19 — — CN disclosed
WO-2022156189-A1 USE OF POLYPEPTIDE COMPOUND IN PREVENTION OR TREATMENT OF INFLAMMATORY BOWEL DISEASE AND INTESTINAL FIBROSIS RELATED THERETO 深圳市图微安创科技开发有限公司 2022-07-28 — — WO disclosed
CN-111278853-B Treatment of biliary cirrhosis based on oxyntomodulin analog GLP-1R/GCGR dual-target agonist polypeptide 深圳市图微安创科技开发有限公司 2022-06-21 — — CN disclosed
CN-114585640-A GLP-1R/GCGR double-target agonist polypeptide derivative for treating viral hepatitis-related liver fibrosis 深圳市图微安创科技开发有限公司 2022-06-03 — — CN disclosed
WO-2022061924-A1 GLP-1R/GCGR DUAL-TARGET AGONIST PEPTIDE DERIVATIVES FOR TREATMENT OF VIRAL HEPATITIS-RELATED HEPATIC FIBROSIS 深圳市图微安创科技开发有限公司 2022-03-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11419918-B2 Treatment of biliary cirrhosis based on oxyntomodulin analogue GLP-1R/GCGR dual-target agonist peptide GCGR, GLP1R, GIPR GLP1R 2/4885SCTR 11/4885
US-20240174728-A1 A USE OF A POLYPEPTIDE COMPOUND IN THE PREPARATION OF DRUGS FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASES AND RELATED INTESTINAL FIBROSIS VIP, FN1, COL14A1 GLP1R 114/4885SCTR 71/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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