Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 10/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.59 |
| ▸ | TNF | P01375 | 2/20 | 0.59 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.59 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.59 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.59 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.59 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.57 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29272646 | 1.00 | BRD4 (1.00) | BRD4MEN1POLBKMT2AACMSD | |
| SCHEMBL29554397 | 0.91 | BRD4 (0.83) | BRD4MEN1POLBKMT2AACMSD | |
| SCHEMBL29272643 | 0.91 | BRD4 (0.83) | BRD4MEN1POLBKMT2AACMSD | |
| SCHEMBL29272638 | 0.90 | BRD4 (1.00) | BRD4MEN1POLBKMT2AACMSD | |
| SCHEMBL29272644 | 0.89 | BRD4 (1.00) | BRD4MEN1POLBKMT2AACMSD | |
| SCHEMBL23892607 | 0.86 | ACMSD (0.79) | BRD4MEN1POLBKMT2AACMSD | |
| SCHEMBL29272622 | 0.84 | BRD4 (1.00) | BRD4MEN1POLBKMT2ACXCR2 | |
| SCHEMBL23892718 | 0.84 | ACMSD (0.75) | BRD4MEN1POLBKMT2AACMSD | |
| SCHEMBL29272636 | 0.84 | BRD4 (1.00) | BRD4MEN1POLBKMT2ATNF | |
| SCHEMBL20099427 | 0.82 | MEN1 (0.78) | BRD4MEN1POLBKMT2AACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114409603-B | Pyrimidinone thioether compound and application thereof | 中国药科大学 | 2023-11-07 | — | — | CN | disclosed |
| CN-114409603-A | Pyrimidone thioether compound and application thereof | 中国药科大学 | 2022-04-29 | — | — | CN | disclosed |