SCHEMBL295574

SCHEMBL295574

CCOC(=O)ON=NOC(=O)OCC

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.63
SOAT1 P35610 1/20 0.57
ALOX15 P16050 1/20 0.50
LMNA P02545 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
MAPT P10636 1/20 0.40
TRPA1 O75762 1/20 0.40
HCAR2 Q8TDS4 1/20 0.36
TSHR P16473 2/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.34
GLO1 Q04760 1/20 0.34
CYP1A2 P05177 1/20 0.34
KDM4E B2RXH2 1/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6586254 0.91 ALDH1A1 (0.52) ALDH1A1SOAT1ALOX15LMNAHSD17B10
SCHEMBL26126849 0.79
SCHEMBL3673 0.78
SCHEMBL1332089 0.78
SCHEMBL1958756 0.78 ALDH1A1 (1.00) ALDH1A1SOAT1ALOX15LMNAHSD17B10
SCHEMBL8298480 0.77 ALDH1A1 (0.55) ALDH1A1SOAT1ALOX15LMNAHSD17B10
SCHEMBL8205738 0.77 ALDH1A1 (0.55) ALDH1A1SOAT1ALOX15LMNAHSD17B10
Charcoal, Activated SCHEMBL1901032 0.76
Water SCHEMBL22362219 0.76
Bromide SCHEMBL10459370 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 623 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2152265-B1 NEW METHOD FOR PREPARING ISOFAGOMINE AND ITS DERIVATIVES AMICUS THERAPEUTICS INC (US) 2014-06-04 EP claimed
EP-2281822-B1 New dihydroindolone derivatives, method of preparing same and pharmaceutical compositions containing them SERVIER LAB (FR) 2013-01-16 EP claimed
EP-1037880-B1 RETINOIC ACID MIMETIC ANILIDES JANSSEN PHARMACEUTICA NV (BE) 2004-06-30 EP claimed
EP-0907650-B1 N- 4-(HETEROARYLMETHYL)PHENYL]-HETEROARYLAMINES JANSSEN PHARMACEUTICA NV (BE) 2002-12-04 EP claimed
EP-0888292-B1 TRICYCLIC COMPOUNDS HAVING ACTIVITY SPECIFIC FOR INTEGRINS, PARTICULARLY ALPHAvBETA3 INTEGRINS, METHOD FOR PREPARING SAME, INTERMEDIATES THEREFOR, USE OF SAID COMPOUNDS AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AVENTIS PHARMA SA (FR) 2001-10-31 EP claimed
EP-0835254-B1 OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE SYNTHELABO (FR) 1999-09-01 EP claimed
EP-0435152-B1 Process for the enantioselective preparation of (omega-1)-hydroxyalkylxanthines HOECHST AG (DE) 1996-11-13 EP claimed
WO-1996017859-A1 PROCESS FOR PREPARING ISOURSODESOXYCHOLIC ACID DR. FALK PHARMA GMBH (DE) 1996-06-13 WO claimed
EP-0435153-B1 R-(-)-1-(5-hydroxyhexyl)-3-methyl-7-propylxanthin, process for its preparation and medicines containing it HOECHST AG (DE) 1996-04-24 EP claimed
EP-0435381-B1 Antipicornaviral pyridazinamines JANSSEN PHARMACEUTICA NV (BE) 1995-11-02 EP claimed
EP-0581095-A2 Substituted acrylic acid esters and plant-protecting agents containing them BASF Aktiengesellschaft (DE) 1994-02-02 EP claimed
EP-0380217-B1 BIS-AZA-BICYCLIC ANXIOLYTIC AGENTS AND ANTIDEPRESSANTS PFIZER INC. (US) 1992-11-19 EP claimed
EP-0192218-B1 PRINTABLE COMPOSITION FOR MAKING EMBOSSED DECORATIVE SHEETS CONGOLEUM CORPORATION (US) 1991-08-07 EP claimed
EP-0435152-A2 Process for the enantioselective preparation of (omega-1)-hydroxyalkylxanthines HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-03 EP claimed
EP-0435153-A2 R-(-)-1-(5-hydroxyhexyl)-3-methyl-7-propylxanthin, process for its preparation and medicines containing it HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-03 EP claimed
EP-0150036-A1 Azolyl-aryl-alkanole-derivatives, processes for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1985-07-31 EP claimed
CN-116162122-B Dehydroepiandrosterone triazole derivative and preparation method and application thereof 郑州工程技术学院 2025-03-28 CN disclosed
CN-116102608-B Stigmasterol triazole derivative and preparation method and application thereof 郑州工程技术学院 2025-03-28 CN disclosed
EP-0081719-A2 2-Nitro-imidazols F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1983-06-22 EP disclosed
EP-0045837-A1 Reactive derivatives of 3-oxa-bicyclo(4.3.0)-non-1-ene-9-one, process for their preparation and their use Dr. Willmar Schwabe GmbH & Co. (DE) 1982-02-17 EP disclosed