Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | APP | P05067 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | USP1 | O94782 | 1/20 | 0.53 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.53 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | USP10 | Q14694 | 1/20 | 0.50 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.50 |
| ▸ | USP13 | Q92995 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29558388 | 0.89 | APP (0.56) | MEN1KMT2AMAPTLMNAAPP | |
| SCHEMBL28725369 | 0.89 | APP (0.56) | MEN1KMT2AMAPTLMNAAPP | |
| SCHEMBL29558267 | 0.84 | LMNA (0.56) | MEN1KMT2AMAPTLMNAAPP | |
| SCHEMBL29558517 | 0.84 | KDM4E (0.49) | MEN1KMT2AMAPTLMNAAPP | |
| SCHEMBL17432180 | 0.84 | RAD52 (0.65) | MEN1KMT2AMAPTLMNAAPP | |
| SCHEMBL29558251 | 0.83 | MAPT (0.49) | MEN1KMT2AMAPTLMNAAPP | |
| SCHEMBL29558864 | 0.81 | APP (0.63) | KMT2AAPPKDM4EPOLBUSP1 | |
| SCHEMBL19553913 | 0.80 | APP (0.61) | MEN1KMT2AMAPTLMNAAPP | |
| SCHEMBL2590855 | 0.79 | RAD52 (0.82) | MEN1KMT2AMAPTLMNAAPP | |
| SCHEMBL23657552 | 0.79 | KDM4E (0.53) | MEN1KMT2AMAPTLMNAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380753-A | Aryl or heteroaryl substituted quinoxaline-2, 3-diamine compound and antibacterial application thereof | 中国医学科学院药物研究所 | 2022-04-22 | — | — | CN | claimed |
| CN-114380753-A | Aryl or heteroaryl substituted quinoxaline-2, 3-diamine compound and antibacterial application thereof | 中国医学科学院药物研究所 | 2022-04-22 | — | — | CN | disclosed |