Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28495200 | 0.86 | HDAC1 (0.60) | HDAC1HDAC6MAPTMEN1KMT2A | |
| SCHEMBL29558833 | 0.86 | HDAC1 (0.60) | HDAC1HDAC6MAPTMEN1KMT2A | |
| SCHEMBL28509075 | 0.84 | HDAC6 (1.00) | HDAC1HDAC6MAPTMEN1KMT2A | |
| SCHEMBL28495879 | 0.82 | HDAC1 (0.68) | HDAC1HDAC6MAPTMEN1KMT2A | |
| SCHEMBL28502726 | 0.75 | HDAC1 (0.70) | HDAC1HDAC6MAPTMEN1KMT2A | |
| SCHEMBL28504884 | 0.75 | HDAC6 (0.75) | HDAC1HDAC6MAPTMEN1KMT2A | |
| SCHEMBL29558498 | 0.73 | HDAC6 (0.71) | HDAC1HDAC6MAPTMEN1KMT2A | |
| SCHEMBL28495211 | 0.72 | HDAC1 (0.78) | HDAC1HDAC6MEN1KMT2APOLB | |
| SCHEMBL11564875 | 0.71 | HCAR3 (0.56) | HDAC1HDAC6MAPTHSD17B10 | |
| SCHEMBL7930570 | 0.69 | HDAC1 (0.48) | HDAC1HDAC6MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111943892-B | Histone deacetylase subtype inhibitor thioacetylarylamine compound and application thereof | 上海中泽医药科技有限公司 | 2022-04-05 | — | — | CN | disclosed |