SCHEMBL29559261

SCHEMBL29559261

C=C(C)c1ccc(C#N)cc1[N+](=O)[O-]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 3/20 0.55
MAPT P10636 7/20 0.47
KMT2A Q03164 3/20 0.47
RAB9A P51151 1/20 0.44
KAT2B Q92831 1/20 0.43
FBP1 P09467 1/20 0.42
MEN1 O00255 2/20 0.41
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
CCR6 P51684 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22897822 1.00 VCAM1 (0.55) VCAM1MAPTKMT2ARAB9AKAT2B
SCHEMBL1799899 0.84 VCAM1 (0.51) VCAM1MAPTKMT2ARAB9AKAT2B
SCHEMBL8488311 0.81 VCAM1 (0.63) VCAM1MAPTKMT2ARAB9AKAT2B
SCHEMBL1886794 0.81 VCAM1 (0.58) VCAM1MAPTKMT2AKAT2BMEN1
SCHEMBL22897632 0.80 ESR1 (0.42) MAPTKMT2AMAPK1HPGDNPSR1
SCHEMBL1734940 0.80 VCAM1 (0.50) VCAM1MAPTKMT2AMEN1MAOA
SCHEMBL8489417 0.80 VCAM1 (0.50) VCAM1MAPTKMT2ARAB9AKAT2B
SCHEMBL1888359 0.79 VCAM1 (0.53) VCAM1MAPTKMT2ARAB9AKAT2B
SCHEMBL16959331 0.78 VCAM1 (0.54) VCAM1MAPTKMT2ARAB9AKAT2B
SCHEMBL22897619 0.77 TSHR (0.45) VCAM1MAPTMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114072000-A Molecules having certain pesticidal effects and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2022-02-18 CN disclosed