SCHEMBL29559552

SCHEMBL29559552

C=C(C)c1ccc(C(=O)OC)cc1[N+](=O)[O-]

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 1/20 0.58
HPGD P15428 4/20 0.50
ALDH1A1 P00352 4/20 0.50
NPSR1 Q6W5P4 1/20 0.50
LMNA P02545 2/20 0.48
POLB P06746 3/20 0.48
KDM4E B2RXH2 2/20 0.48
KMT2A Q03164 3/20 0.47
MEN1 O00255 1/20 0.47
GLA P06280 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
CASP1 P29466 1/20 0.46
CASP7 P55210 1/20 0.46
ATM Q13315 1/20 0.46
HSD17B10 Q99714 1/20 0.46
PKM P14618 1/20 0.46
ERN1 O75460 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22897788 1.00 VCAM1 (0.58) VCAM1HPGDALDH1A1NPSR1LMNA
SCHEMBL8000314 0.88 VCAM1 (0.61) VCAM1HPGDALDH1A1NPSR1LMNA
SCHEMBL559830 0.88 VCAM1 (0.64) VCAM1HPGDALDH1A1NPSR1LMNA
SCHEMBL30525281 0.88 VCAM1 (0.64) VCAM1HPGDALDH1A1NPSR1LMNA
Methane SCHEMBL27578247 0.86 VCAM1 (0.62) VCAM1HPGDALDH1A1NPSR1LMNA
SCHEMBL2116235 0.85 VCAM1 (0.61) VCAM1HPGDALDH1A1NPSR1LMNA
SCHEMBL5548331 0.85 VCAM1 (0.54) VCAM1HPGDALDH1A1NPSR1LMNA
SCHEMBL22897616 0.84 MAPT (0.51) VCAM1ALDH1A1LMNAPOLBKMT2A
SCHEMBL29559260 0.84 MAPT (0.51) VCAM1ALDH1A1LMNAPOLBKMT2A
SCHEMBL22897619 0.84 TSHR (0.45) VCAM1ALDH1A1LMNAPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114072000-A Molecules having certain pesticidal effects and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2022-02-18 CN disclosed