Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | S100B | P04271 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9782622 | 0.90 | ALDH1A1 (0.59) | NR3C2ALDH1A1TSHRHSD17B10L3MBTL1 | |
| SCHEMBL27315184 | 0.88 | ALDH1A1 (0.62) | NR3C2ALDH1A1TSHRHSD17B10L3MBTL1 | |
| SCHEMBL9513157 | 0.88 | NR3C2 (0.60) | NR3C2ALDH1A1TSHRHSD17B10L3MBTL1 | |
| SCHEMBL9480557 | 0.86 | MEN1 (0.50) | NR3C2ALDH1A1TSHRHSD17B10MAPK1 | |
| SCHEMBL2947867 | 0.86 | MEN1 (0.50) | NR3C2ALDH1A1TSHRHSD17B10MAPK1 | |
| Diphenylamine SCHEMBL2721122 | 0.86 | HSD17B10 (0.60) | NR3C2ALDH1A1TSHRHSD17B10L3MBTL1 | |
| SCHEMBL18432000 | 0.85 | NR3C2 (0.53) | NR3C2ALDH1A1TSHRHSD17B10L3MBTL1 | |
| SCHEMBL17703873 | 0.82 | NR3C2 (0.55) | NR3C2ALDH1A1TSHRHSD17B10L3MBTL1 | |
| SCHEMBL92754 | 0.82 | ALDH1A1 (0.72) | ALDH1A1TSHRHSD17B10L3MBTL1ALOX12 | |
| SCHEMBL585745 | 0.82 | ALDH1A1 (0.72) | ALDH1A1TSHRHSD17B10L3MBTL1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7750156-B2 | Method of producing aminophenol compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-07-06 | — | — | US | claimed |