Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22897899 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1 | |
| SCHEMBL9546811 | 0.83 | CYP3A4 (0.47) | SMN1; SMN2TSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL18184993 | 0.82 | TSHR (0.51) | SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1 | |
| SCHEMBL18184948 | 0.79 | TSHR (0.49) | SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1 | |
| SCHEMBL18184998 | 0.79 | TSHR (0.55) | SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1 | |
| SCHEMBL18184962 | 0.78 | TSHR (0.50) | SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1 | |
| SCHEMBL18184988 | 0.77 | TSHR (0.46) | SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1 | |
| SCHEMBL16920872 | 0.75 | S1PR4 (0.40) | SMN1; SMN2TSHRL3MBTL1ALDH1A1MAPT | |
| SCHEMBL18184975 | 0.75 | TSHR (0.50) | SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1 | |
| SCHEMBL10106284 | 0.74 | TSHR (0.62) | SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072000-A | Molecules having certain pesticidal effects and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2022-02-18 | — | — | CN | disclosed |