Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 18/20 | 0.58 |
| ▸ | CPT2 | P23786 | 1/20 | 0.47 |
| ▸ | CPT1A | P50416 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29562178 | 0.86 | USP30 (0.63) | USP30CPT2CPT1A | |
| SCHEMBL29562461 | 0.85 | USP30 (0.64) | USP30CPT2CPT1A | |
| SCHEMBL19384996 | 0.82 | USP30 (0.85) | USP30 | |
| SCHEMBL29563528 | 0.77 | USP30 (0.57) | USP30 | |
| SCHEMBL29563291 | 0.76 | USP30 (0.82) | USP30 | |
| SCHEMBL22555637 | 0.76 | USP30 (0.82) | USP30 | |
| SCHEMBL29562882 | 0.72 | USP30 (0.70) | USP30 | |
| SCHEMBL29679852 | 0.71 | USP30 (0.59) | USP30CPT2CPT1A | |
| SCHEMBL29563356 | 0.70 | USP30 (0.59) | USP30 | |
| SCHEMBL28592627 | 0.70 | USP30 (0.48) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3433246-B1 | 1-CYANO-PYRROLIDINE DERIVATIVES AS DBU INHIBITORS | MISSION THERAPEUTICS LTD (GB) | 2022-05-04 | — | — | EP | disclosed |