Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 16/20 | 0.70 |
| ▸ | PIM1 | P11309 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29562302 | 0.89 | USP30 (0.68) | USP30 | |
| SCHEMBL19400795 | 0.82 | USP30 (1.00) | USP30 | |
| SCHEMBL29562648 | 0.79 | USP30 (0.65) | USP30 | |
| SCHEMBL29562274 | 0.76 | USP30 (0.66) | USP30DRD2DRD4 | |
| SCHEMBL29562251 | 0.75 | USP30 (0.44) | USP30 | |
| SCHEMBL29562224 | 0.72 | USP30 (0.58) | USP30 | |
| SCHEMBL19385256 | 0.71 | USP30 (1.00) | USP30 | |
| SCHEMBL9559820 | 0.68 | CHRNA7 (0.61) | USP30 | |
| SCHEMBL29563528 | 0.67 | USP30 (0.57) | USP30 | |
| SCHEMBL22555637 | 0.66 | USP30 (0.82) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3433246-B1 | 1-CYANO-PYRROLIDINE DERIVATIVES AS DBU INHIBITORS | MISSION THERAPEUTICS LTD (GB) | 2022-05-04 | — | — | EP | disclosed |