Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 20/20 | 0.66 |
| ▸ | VEGFA | P15692 | 5/20 | 0.66 |
| ▸ | FLT1 | P17948 | 5/20 | 0.66 |
| ▸ | EGLN3 | Q9H6Z9 | 4/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921233 | 1.00 | EGLN1 (0.66) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL14150648 | 0.87 | EGLN1 (0.55) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL1921373 | 0.87 | EGLN1 (0.52) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL23501734 | 0.85 | EGLN1 (0.73) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL23199578 | 0.85 | EGLN1 (0.63) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL1920739 | 0.83 | EGLN1 (0.67) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL24405262 | 0.83 | EGLN1 (0.57) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL1921346 | 0.81 | EGLN1 (0.54) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL1922631 | 0.81 | EGLN1 (0.72) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL24405118 | 0.81 | EGLN1 (0.79) | EGLN1VEGFAFLT1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078428-A1 | COMPOUND AS PROLYL HYDROXYLASE INHIBITOR AND PREPARATION METHOD THEREFOR | 江苏苏中药业集团股份有限公司 | 2022-04-21 | — | — | WO | disclosed |