SCHEMBL29563323

SCHEMBL29563323

N#CN1CCCC1c1cc(-c2cccc(-c3ccccc3)c2)no1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ USP30 Q70CQ3 19/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19400851 0.81 USP30 (1.00) USP30
SCHEMBL29562278 0.81 USP30 (1.00) USP30
SCHEMBL19385044 0.79 USP30 (0.62) USP30
SCHEMBL19400903 0.78 USP30 (1.00) USP30
SCHEMBL19400902 0.78 USP30 (1.00) USP30
SCHEMBL29562648 0.77 USP30 (0.65) USP30
SCHEMBL19400798 0.76 USP30 (1.00) USP30
SCHEMBL19400814 0.75 USP30 (1.00) USP30
SCHEMBL29679735 0.75 USP30 (0.62) USP30
SCHEMBL22555637 0.74 USP30 (0.82) USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3433246-B1 1-CYANO-PYRROLIDINE DERIVATIVES AS DBU INHIBITORS MISSION THERAPEUTICS LTD (GB) 2022-05-04 — — EP disclosed
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