SCHEMBL29562648

SCHEMBL29562648

N#CN1CCCC1c1cc(-c2cccc(-c3ccccc3)c2)n[nH]1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ USP30 Q70CQ3 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29562302 0.88 USP30 (0.68) USP30
SCHEMBL29562274 0.85 USP30 (0.66) USP30
SCHEMBL19400758 0.79 USP30 (1.00) USP30
SCHEMBL29562882 0.79 USP30 (0.70) USP30
SCHEMBL29562178 0.78 USP30 (0.63) USP30
SCHEMBL19385162 0.77 USP30 (1.00) USP30
SCHEMBL29563323 0.77 USP30 (0.69) USP30
SCHEMBL29562358 0.76 USP30 (0.69) USP30
SCHEMBL19400814 0.75 USP30 (1.00) USP30
SCHEMBL22555615 0.75 USP30 (1.00) USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3433246-B1 1-CYANO-PYRROLIDINE DERIVATIVES AS DBU INHIBITORS MISSION THERAPEUTICS LTD (GB) 2022-05-04 — — EP disclosed
Send feedback