SCHEMBL29564016

SCHEMBL29564016

Nc1cccc(-c2ccccc2)c1N

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.68
HSD17B10 Q99714 3/20 0.68
L3MBTL1 Q9Y468 1/20 0.50
MAPT P10636 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.43
CYP3A4 P08684 2/20 0.43
ALOX15 P16050 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
DPP4 P27487 1/20 0.43
MAP4K4 O95819 1/20 0.42
CSF1R P07333 1/20 0.42
FGFR1 P11362 1/20 0.42
PDGFRA P16234 1/20 0.42
LTK P29376 1/20 0.42
KDR P35968 1/20 0.42
MAPK8 P45983 1/20 0.42
CSNK1A1 P48729 1/20 0.42
LIMK1 P53667 1/20 0.42
CDK5 Q00535 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169282 1.00 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1MAPTSMN1; SMN2
Biphenyl SCHEMBL29177662 0.98 ALDH1A1 (0.65) ALDH1A1HSD17B10L3MBTL1MAPTSMN1; SMN2
SCHEMBL27599082 0.98 ALDH1A1 (0.65) ALDH1A1HSD17B10L3MBTL1MAPTSMN1; SMN2
Methane SCHEMBL2458338 0.98 ALDH1A1 (0.65) ALDH1A1HSD17B10L3MBTL1MAPTSMN1; SMN2
Fluoride SCHEMBL29111498 0.98 ALDH1A1 (0.65) ALDH1A1HSD17B10L3MBTL1MAPTSMN1; SMN2
Hydrochloric Acid SCHEMBL9614559 0.98 ALDH1A1 (0.65) ALDH1A1HSD17B10L3MBTL1MAPTSMN1; SMN2
Water SCHEMBL6830763 0.98 ALDH1A1 (0.65) ALDH1A1HSD17B10L3MBTL1MAPTSMN1; SMN2
SCHEMBL10909218 0.98 ALDH1A1 (0.65) ALDH1A1HSD17B10L3MBTL1MAPTSMN1; SMN2
Hydrochloric Acid SCHEMBL10595671 0.98 ALDH1A1 (0.65) ALDH1A1HSD17B10L3MBTL1MAPTSMN1; SMN2
Ammonia Solution, Strong SCHEMBL18172272 0.98 ALDH1A1 (0.65) ALDH1A1HSD17B10L3MBTL1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024201308-A1 NOVEL BENZIMIDAZOLONE DERIVATIVE COMPOUND AS AUTOTAXIN INHIBITOR 주식회사 엘지화학 2024-10-03 WO disclosed
CN-113563344-B Carbazole derivative, organic electroluminescent material, light-emitting element, and consumer product 北京八亿时空液晶科技股份有限公司 2023-11-21 CN disclosed
CN-117069642-A Novel free radical monomer containing 2-aminodiphenylamine structure and polymer, preparation method and application thereof 武汉理工大学 2023-11-17 CN disclosed
CN-115260512-B Method for directly synthesizing single-component covalent organic framework aerogel 四川大学 2023-06-13 CN disclosed
EP-4081199-A2 LIPOXYGENASE INHIBITORS SRI International (US) 2022-11-02 EP disclosed