Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dextrocarnitine SCHEMBL28909100 | 0.81 | MAPT (0.79) | MAPTSLC22A16LMNASMN1; SMN2SLC22A6 | |
| SCHEMBL339065 | 0.79 | CHRM5 (0.44) | MAPTLMNASMN1; SMN2CHRM1CHRM3 | |
| Glycerin SCHEMBL9060924 | 0.78 | SMN1; SMN2 (0.45) | MAPTLMNASMN1; SMN2CHRM1CHRM3 | |
| SCHEMBL28176595 | 0.77 | CHRM5 (0.43) | MAPTLMNASMN1; SMN2CHRM1CHRM3 | |
| Levocarnitine SCHEMBL374454 | 0.77 | MAPT (0.95) | MAPTSLC22A16LMNASMN1; SMN2SLC22A6 | |
| Dextrocarnitine SCHEMBL1069009 | 0.77 | MAPT (0.95) | MAPTSLC22A16LMNASMN1; SMN2SLC22A6 | |
| Levocarnitine SCHEMBL13034193 | 0.77 | MAPT (0.95) | MAPTSLC22A16LMNASMN1; SMN2SLC22A6 | |
| Levocarnitine SCHEMBL23045915 | 0.75 | MAPT (0.91) | MAPTSLC22A16LMNASMN1; SMN2SLC22A6 | |
| Dextrocarnitine SCHEMBL1820591 | 0.75 | MAPT (0.91) | MAPTSLC22A16LMNASMN1; SMN2SLC22A6 | |
| Dextrocarnitine SCHEMBL20447744 | 0.75 | MAPT (0.91) | MAPTSLC22A16LMNASMN1; SMN2SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022073502-A1 | USE OF BIOMARKER IN PREPARATION OF LUNG CANCER DETECTION REAGENT AND RELATED METHOD | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 2022-04-14 | — | — | WO | claimed |
| WO-2022073502-A1 | USE OF BIOMARKER IN PREPARATION OF LUNG CANCER DETECTION REAGENT AND RELATED METHOD | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 2022-04-14 | — | — | WO | disclosed |