Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | SHBG | P04278 | 1/20 | 0.51 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | G6PD | P11413 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15837577 | 1.00 | LMNA (0.51) | LMNAGPBAR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15838019 | 1.00 | LMNA (0.51) | LMNAGPBAR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15953333 | 1.00 | LMNA (0.51) | LMNAGPBAR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15953331 | 1.00 | LMNA (0.51) | LMNAGPBAR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL20081182 | 1.00 | LMNA (0.51) | LMNAGPBAR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18950382 | 1.00 | LMNA (0.51) | LMNAGPBAR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15959577 | 0.89 | LMNA (0.52) | LMNAGPBAR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15837753 | 0.89 | LMNA (0.52) | LMNAGPBAR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15959585 | 0.89 | LMNA (0.52) | LMNAGPBAR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15959419 | 0.89 | LMNA (0.52) | LMNAGPBAR1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605486-A | Neuroactive steroids, prodrugs thereof, and methods of treatment using the same | 华盛顿大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-109970833-B | Neuroactive steroids, prodrugs thereof, and methods of treatment using the same | 华盛顿大学 | 2022-05-27 | — | — | CN | disclosed |