Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 13/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | BRD1 | O95696 | 1/20 | 0.55 |
| ▸ | TAF1 | P21675 | 1/20 | 0.55 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | CRHBP | P24387 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1890453 | 1.00 | MEN1 (0.62) | MEN1KMT2ALMNABRD1TAF1 | |
| SCHEMBL17599254 | 0.88 | MEN1 (0.60) | MEN1KMT2ALMNABRD1TAF1 | |
| SCHEMBL1896021 | 0.85 | MEN1 (0.59) | MEN1KMT2ALMNABRD1TAF1 | |
| SCHEMBL11675290 | 0.85 | MEN1 (0.59) | MEN1KMT2ALMNABRD1TAF1 | |
| SCHEMBL7712239 | 0.84 | MEN1 (0.72) | MEN1KMT2ALMNABRD1TAF1 | |
| SCHEMBL16784368 | 0.84 | MEN1 (0.68) | MEN1KMT2ALMNABRD1TAF1 | |
| SCHEMBL7706747 | 0.84 | BRD1 (0.56) | MEN1KMT2ALMNABRD1TAF1 | |
| SCHEMBL25036803 | 0.82 | MEN1 (0.47) | MEN1KMT2ALMNABRD1TAF1 | |
| SCHEMBL18648444 | 0.81 | MEN1 (0.64) | MEN1KMT2ALMNABRD1TAF1 | |
| SCHEMBL16773474 | 0.81 | MEN1 (0.64) | MEN1KMT2ALMNABRD1TAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112375066-B | 1, 8-naphthalic anhydride derivatives containing 8- (benzoylamino) quinoline and synthesis and application thereof | 大连理工大学 | 2022-05-27 | — | — | CN | claimed |
| CN-112375066-B | 1, 8-naphthalic anhydride derivatives containing 8- (benzoylamino) quinoline and synthesis and application thereof | 大连理工大学 | 2022-05-27 | — | — | CN | disclosed |