Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 13/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.68 |
| ▸ | LMNA | P02545 | 6/20 | 0.68 |
| ▸ | BRD1 | O95696 | 2/20 | 0.64 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.64 |
| ▸ | TAF1 | P21675 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28588259 | 0.88 | MEN1 (0.67) | MEN1KMT2ALMNABRD1BRPF1 | |
| SCHEMBL7712239 | 0.86 | MEN1 (0.72) | MEN1KMT2ALMNABRD1BRPF1 | |
| SCHEMBL18648444 | 0.85 | MEN1 (0.64) | MEN1KMT2ALMNABRD1BRPF1 | |
| SCHEMBL16773474 | 0.85 | MEN1 (0.64) | MEN1KMT2ALMNABRD1BRPF1 | |
| SCHEMBL1896021 | 0.84 | MEN1 (0.59) | MEN1KMT2ALMNABRD1BRPF1 | |
| SCHEMBL11675290 | 0.84 | MEN1 (0.59) | MEN1KMT2ALMNABRD1BRPF1 | |
| SCHEMBL29564392 | 0.84 | MEN1 (0.62) | MEN1KMT2ALMNABRD1BRPF1 | |
| SCHEMBL1890453 | 0.84 | MEN1 (0.62) | MEN1KMT2ALMNABRD1BRPF1 | |
| SCHEMBL22699960 | 0.83 | MEN1 (0.80) | MEN1KMT2ALMNABRD1BRPF1 | |
| SCHEMBL28197565 | 0.83 | HDAC6 (0.64) | MEN1KMT2ALMNABRD1BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220401474-A1 | HDAC6-ACTIVATED MACROPHAGES, COMPOSITIONS, AND USES THEREOF | MEDSTAR HEALTH | 2022-12-22 | — | — | US | disclosed |
| US-9597344-B2 | Sonosensitive liposome, pharmaceutical composition including the same, and method of delivering active agent to subject using the sonosensitive liposome | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-03-21 | — | — | US | disclosed |
| US-9220718-B2 | Sonosensitive liposome, pharmaceutical composition including the same, and method of delivering active agent to subject using the sonosensitive liposome | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2015-12-29 | — | — | US | disclosed |
| US-20150352039-A1 | SONOSENSITIVE LIPOSOME, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND METHOD OF DELIVERING ACTIVE AGENT TO SUBJECT USING THE SONOSENSITIVE LIPOSOME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2015-12-10 | — | — | US | disclosed |
| US-20150150971-A1 | SONOSENSITIVE LIPOSOME, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND METHOD OF DELIVERING ACTIVE AGENT TO SUBJECT USING THE SONOSENSITIVE LIPOSOME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220401474-A1 | HDAC6-ACTIVATED MACROPHAGES, COMPOSITIONS, AND USES THEREOF | HDAC6, HDAC1, HDAC3 | MEN1 4507/4885KMT2A 200/4885LMNA 3602/4885 |
| US-20150150971-A1 | SONOSENSITIVE LIPOSOME, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND METHOD OF DELIVERING ACTIVE AGENT TO SUBJECT USING THE SONOSENSITIVE LIPOSOME | SON, LIPA, LIPE | MEN1 645/4885KMT2A 4705/4885LMNA 501/4885 |
| US-20150352039-A1 | SONOSENSITIVE LIPOSOME, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND METHOD OF DELIVERING ACTIVE AGENT TO SUBJECT USING THE SONOSENSITIVE LIPOSOME | SON, LIPA, LIPE | MEN1 645/4885KMT2A 4705/4885LMNA 501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.