Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 16/20 | 0.52 |
| ▸ | MTOR | P42345 | 12/20 | 0.52 |
| ▸ | PIK3R1 | P27986 | 10/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | RICTOR | Q6R327 | 2/20 | 0.47 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.47 |
| ▸ | MAPKAP1 | Q9BPZ7 | 2/20 | 0.47 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.46 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7925159 | 0.92 | PIK3CA (0.59) | PIK3CAMTORPIK3R1PIK3CDPIK3CB | |
| SCHEMBL1309410 | 0.88 | POLB (0.54) | PIK3CAMTORPIK3R1POLBPIK3CD | |
| SCHEMBL31147112 | 0.85 | PIK3CA (0.52) | PIK3CAMTORPIK3R1PIK3CDPIK3CB | |
| SCHEMBL1309279 | 0.80 | PIK3CA (0.61) | PIK3CAMTORPIK3R1POLBPIK3CD | |
| SCHEMBL15386450 | 0.78 | PIK3CA (0.84) | PIK3CAMTORPIK3R1POLBPIK3CD | |
| SCHEMBL29434917 | 0.78 | PIK3CA (0.84) | PIK3CAMTORPIK3R1POLBPIK3CD | |
| SCHEMBL777894 | 0.78 | HRH1 (0.55) | PIK3CAMTORPIK3R1POLBPIK3CD | |
| SCHEMBL30805488 | 0.76 | PIK3CA (0.83) | PIK3CAMTORPIK3R1POLBPIK3CD | |
| SCHEMBL1309314 | 0.76 | PIK3CA (0.57) | PIK3CAMTORPIK3R1PIK3CDPIK3CB | |
| SCHEMBL778162 | 0.76 | HRH1 (0.65) | PIK3CAMTORPIK3R1POLBPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220135551-A1 | TREATMENT OF NEUROLOGICAL DISORDERS | PIQUR THERAPEUTICS AG (CH) | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135551-A1 | TREATMENT OF NEUROLOGICAL DISORDERS | CHRM1, CHRM2, C1R | PIK3CA 4513/4885MTOR 4473/4885PIK3R1 3948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.