Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 4/20 | 0.45 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29564998 | 0.84 | NT5E (0.44) | NT5EPBRM1 | |
| SCHEMBL29829678 | 0.84 | NT5E (0.51) | NT5ELRRK2ALDH1A1PBRM1 | |
| SCHEMBL29829491 | 0.82 | NT5E (0.51) | NT5EALDH1A1KDM4EHSD17B10PBRM1 | |
| SCHEMBL24394575 | 0.82 | NT5E (0.54) | NT5E | |
| SCHEMBL29564913 | 0.81 | NT5E (0.48) | NT5EPBRM1 | |
| SCHEMBL29564755 | 0.81 | NT5E (0.46) | NT5E | |
| SCHEMBL29829512 | 0.81 | NT5E (0.48) | NT5E | |
| SCHEMBL29565183 | 0.81 | NT5E (0.47) | NT5ELRRK2ALDH1A1PBRM1 | |
| SCHEMBL29829627 | 0.80 | NT5E (0.48) | NT5ELRRK2PBRM1 | |
| SCHEMBL24394522 | 0.79 | NT5E (0.52) | NT5EALDH1A1PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022090711-A1 | COMPOUNDS AS CD73 INHIBITORS | AdoRx Therapeutics Limited (GB) | 2022-05-05 | — | — | WO | disclosed |