Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 11/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29829391 | 0.94 | NT5E (0.49) | NT5EMAPTKDM4CSPR | |
| SCHEMBL29829678 | 0.89 | NT5E (0.51) | NT5EMAPTKDM4C | |
| SCHEMBL29829627 | 0.84 | NT5E (0.48) | NT5EMAPTKDM4C | |
| SCHEMBL29829491 | 0.83 | NT5E (0.51) | NT5EMAPTKDM4C | |
| SCHEMBL24394575 | 0.82 | NT5E (0.54) | NT5EMAPTKDM4C | |
| SCHEMBL29564913 | 0.82 | NT5E (0.48) | NT5EMAPTKDM4C | |
| SCHEMBL29564755 | 0.82 | NT5E (0.46) | NT5EMAPTKDM4C | |
| SCHEMBL29564749 | 0.81 | NT5E (0.45) | NT5E | |
| SCHEMBL24394522 | 0.80 | NT5E (0.52) | NT5EMAPTKDM4C | |
| SCHEMBL29829241 | 0.80 | NT5E (0.52) | NT5EMAPTKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022195499-A1 | SUBSTITUTED PYRIDAZINE COMPOUNDS AS CD73 INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2022-09-22 | — | — | WO | disclosed |