Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25021784 | 0.88 | MEN1 (0.53) | MEN1KMT2AMAOBNPC1RAB9A | |
| SCHEMBL29565658 | 0.82 | MEN1 (0.49) | MEN1KMT2AMAOBMAPTLMNA | |
| SCHEMBL23422279 | 0.82 | MEN1 (0.49) | MEN1KMT2AMAOBMAPTLMNA | |
| SCHEMBL31031177 | 0.79 | KMT2A (0.47) | MEN1KMT2AMAOBNPC1RAB9A | |
| SCHEMBL11739144 | 0.76 | MAOB (0.59) | MEN1KMT2AMAOBCASP3SENP8 | |
| SCHEMBL26455213 | 0.74 | MAOB (0.54) | MEN1KMT2AMAOBCASP3SENP8 | |
| SCHEMBL11739156 | 0.74 | MAOB (0.59) | MEN1KMT2AMAOBNPC1RAB9A | |
| SCHEMBL31031144 | 0.73 | S1PR5 (0.42) | MEN1KMT2ANPC1RAB9ACASP3 | |
| SCHEMBL2951462 | 0.73 | MEN1 (0.65) | MEN1KMT2AMAOBLMNASLC6A2 | |
| SCHEMBL658101 | 0.72 | MAOB (0.61) | MEN1KMT2AMAOBCASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539044-A | Dehydrated icaritin intermediate compound | 鲁南制药集团股份有限公司 | 2022-05-27 | — | — | CN | disclosed |