Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.49 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30141054 | 1.00 | MAOB (0.61) | MAOBMEN1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL11739144 | 0.92 | MAOB (0.59) | MAOBMEN1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL14178903 | 0.92 | CYP3A4 (0.63) | MAOBMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL14181066 | 0.91 | MAOB (0.68) | MAOBMEN1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL18526952 | 0.91 | MAOB (0.51) | MAOBMEN1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL14616693 | 0.90 | MAOB (0.56) | MAOBMEN1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL30789227 | 0.90 | MAOB (0.56) | MAOBMEN1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL14178921 | 0.87 | MAOB (0.54) | MAOBMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL26455213 | 0.87 | MAOB (0.54) | MAOBMEN1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL10147478 | 0.87 | MAPT (0.53) | MAOBSMN1; SMN2CYP2C19MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048920-A1 | Preparation of (+)-Catechin, (-)-Epicatechin, (-)-Catechin, and (+)-Epicatechin and Their 5,7,3',4'-Tetra-O-Benzyl Analogues | MARS, INCORPORATED (US) | 2010-02-25 | — | — | US | claimed |
| EP-1896443-A1 | PREPARATION OF (+)-CATECHIN, (-)-EPICATECHIN, (-)-CATECHIN, (+)-EPICATECHIN, AND THEIR 5,7,3',4'-TETRA-O-BENZYL ANALOGUES | MARS, INCORPORATED (US) | 2008-03-12 | — | — | EP | claimed |
| WO-2007002877-A1 | PREPARATION OF (+)-CATECHIN, (-)-EPICATECHIN, (-)-CATECHIN, (+)-EPICATECHIN, AND THEIR 5,7,3',4'-TETRA-O-BENZYL ANALOGUES | MARS, INCORPORATED (US) | 2007-01-04 | — | — | WO | claimed |
| EP-2822653-B1 | NEW C-GLYCOSYLPOLYPHENOL ANTIDIABETIC AGENTS, EFFECT ON GLUCOSE TOLERANCE AND INTERACTION WITH BETA-AMYLOID. THERAPEUTIC APPLICATIONS OF THE SYNTHESIZED AGENT(S) AND OF GENISTA TENERA ETHYL ACETATE EXTRACTS CONTAINING SOME OF THOSE AGENTS | FACULDADE DE CIENCIAS DA UNIV DE LISBOA (PT) | 2024-06-19 | — | — | EP | disclosed |
| CN-117794526-A | Compositions and methods for antioxidants and anti-inflammatory therapeutics | 阿万蒂生物科学股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-113710262-B | Scutellaria baicalensis composition and method for taste modulation | 国际香料和香精公司 | 2024-01-05 | — | — | CN | disclosed |
| US-20230053152-A1 | Novel Quercetin Redox Derivative And Use Thereof As BET Inhibitor | BENOBIO CO., LTD. (KR) | 2023-02-16 | — | — | US | disclosed |
| WO-2023288020-A1 | COMPOSITIONS AND METHODS FOR ANTIOXIDANT AND ANTI-INFLAMMATORY THERAPEUTICS | AVANTI BIOSCIENCES INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| CN-113710262-A | Scutellaria baicalensis composition and method for taste modulation | 国际香料和香精公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-112724114-A | Epicatechin and related polyphenols | 斯法尔制药私人有限公司 | 2021-04-30 | — | — | CN | disclosed |
| EP-2981260-B1 | NOVEL ANALOGUES OF EPICATECHIN AND RELATED POLYPHENOLS | SPHAERA PHARMA PRIVATE LTD (IN) | 2021-01-13 | — | — | EP | disclosed |
| US-20040029914-A1 | Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents | SRI INTERNATIONAL | 2004-02-12 | — | — | US | disclosed |
| US-20030229136-A1 | Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents | SRI INTERNATIONAL | 2003-12-11 | — | — | US | disclosed |
| WO-2003089423-A2 | NOVEL FLAVANOIDS AND CHALCONES AS CHEMOTHERAPEUTIC, CHEMOPREVENTIVE, AND ANTIANGIOGENIC AGENTS | SRI INTERNATIONAL (US) | 2003-10-30 | — | — | WO | disclosed |
| US-4348333-A | β-Ketocarboxyl and phosphonate dihydro-chalcone sweeteners | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1982-09-07 | — | — | US | disclosed |
| US-4290957-A | SWEETENERS | DYNAPOL (US) | 1981-09-22 | — | — | US | disclosed |
| US-4283434-A | FOR FOODS | NUTRASWEET COMPANY THE | 1981-08-11 | — | — | US | disclosed |
| US-4267165-A | Comestibles sweetened with alpha amino acid dihydrochalcones | DYNAPOL (US) | 1981-05-12 | — | — | US | disclosed |
| US-4226804-A | ARTIFICIAL SWEETENER | DYNAPOL (US) | 1980-10-07 | — | — | US | disclosed |
| US-4204007-A | 4-(Dihydroxyhexoxy)dihydrochalcone sweeteners | DYNAPOL (US) | 1980-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029914-A1 | Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents | FLT1, VEGFA, FLT4 | MAOB 1380/4885MEN1 3385/4885KMT2A 3690/4885 |
| US-20030229136-A1 | Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents | FLT1, VEGFA, FLT4 | MAOB 1370/4885MEN1 3434/4885KMT2A 3666/4885 |
| US-20100048920-A1 | Preparation of (+)-Catechin, (-)-Epicatechin, (-)-Catechin, and (+)-Epicatechin and Their 5,7,3',4'-Tetra-O-Benzyl Analogues | HAAO, TES, HPD | MAOB 882/4885MEN1 4540/4885KMT2A 2842/4885 |
| US-20230053152-A1 | Novel Quercetin Redox Derivative And Use Thereof As BET Inhibitor | BET1, BRD4, BRD3 | MAOB 1784/4885MEN1 4278/4885KMT2A 884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.