Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 3/20 | 1.00 |
| ▸ | XDH | P47989 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25326934 | 1.00 | F11 (1.00) | F11XDHCYP1A2PIN1ALDH1A1 | |
| SCHEMBL26108356 | 0.87 | F11 (0.77) | F11XDHPIN1SLC22A12GRIA2 | |
| SCHEMBL26107862 | 0.87 | F11 (0.77) | F11XDHCYP1A2PIN1ALDH1A1 | |
| SCHEMBL25325875 | 0.84 | F11 (0.72) | F11XDHALDH1A1 | |
| SCHEMBL25326695 | 0.84 | F11 (0.72) | F11XDHPIN1SLC22A12GRIA2 | |
| SCHEMBL30771632 | 0.84 | F11 (0.72) | F11XDHPIN1SLC22A12GRIA2 | |
| SCHEMBL28746467 | 0.83 | F11 (0.71) | F11XDHCYP1A2ALDH1A1PKM | |
| SCHEMBL25327264 | 0.81 | F11 (0.67) | F11XDHPIN1SLC22A12GRIA2 | |
| SCHEMBL30771625 | 0.81 | F11 (0.67) | F11XDHPIN1SLC22A12GRIA2 | |
| SCHEMBL26109700 | 0.81 | F11 (0.67) | F11XDHPIN1SLC22A12GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105881-B | Platelet aggregation inhibitor, and preparation method and application thereof | 沈阳海诺威医药科技有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-114105881-B | Platelet aggregation inhibitor, and preparation method and application thereof | 沈阳海诺威医药科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-114539158-B | FXIa inhibitor compound and preparation method and application thereof | 沈阳药科大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-114539158-A | FXIa inhibitor compound and preparation method and application thereof | 沈阳药科大学 | 2022-05-27 | — | — | CN | disclosed |