SCHEMBL29565713

SCHEMBL29565713

CC(C)=CCC[C@@H](C)[C@@H]1C=CC(C)=CC1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.40
RORC P51449 1/20 0.37
BID P55957 6/20 0.37
BCL2L1 Q07817 6/20 0.37
MCL1 Q07820 6/20 0.37
BAK1 Q16611 6/20 0.37
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
BCL2 P10415 1/20 0.37
SRC P12931 1/20 0.35
ALDH1A1 P00352 2/20 0.34
ALOX15 P16050 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
NR1H3 Q13133 1/20 0.34
PKM P14618 1/20 0.33
METAP2 P50579 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27974253 1.00 PTPN1 (0.40) PTPN1RORCBIDBCL2L1MCL1
SCHEMBL154620 1.00 PTPN1 (0.40) PTPN1RORCBIDBCL2L1MCL1
SCHEMBL23924349 1.00 PTPN1 (0.40) PTPN1RORCBIDBCL2L1MCL1
SCHEMBL29350001 1.00 PTPN1 (0.40) PTPN1RORCBIDBCL2L1MCL1
Alcohol SCHEMBL3663095 0.96 PTPN1 (0.38) PTPN1RORCBIDBCL2L1MCL1
Rel-Menthone SCHEMBL5961370 0.83 PTPN1 (0.35) PTPN1RORCBIDBCL2L1MCL1
Methyl Salicylate SCHEMBL1579926 0.81 LMNA (0.42) PTPN1BIDBCL2L1MCL1BAK1
SCHEMBL15764699 0.81 PTPN1 (0.35) PTPN1RORCBIDBCL2L1MCL1
Sabinene SCHEMBL9360164 0.79 NR1I2 (0.32) PTPN1RORCBIDBCL2L1MCL1
SCHEMBL30307777 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2714901-B1 PEST RESISTANT PLANTS KEYGENE NV (NL) 2024-09-18 EP claimed
EP-4663761-A2 INSECTICIDAL PROTEINS AND METHODS FOR THEIR USE Pioneer Hi-Bred International, Inc. (US) 2025-12-17 EP disclosed
EP-3244727-B1 INSECTICIDAL PROTEINS AND METHODS FOR THEIR USE PIONEER HI BRED INT (US) 2025-10-22 EP disclosed
CN-114075267-B Insecticidal proteins and methods of use thereof 先锋国际良种公司 2025-03-18 CN disclosed
EP-2714901-B1 PEST RESISTANT PLANTS KEYGENE NV (NL) 2024-09-18 EP disclosed
US-20240271157-A1 INSECTICIDAL PROTEINS AND METHODS FOR THEIR USE PIONEER HI-BRED INTERNATIONAL, INC. (US) 2024-08-15 US disclosed
US-11959090-B2 Insecticidal proteins and methods for their use PIONEER HI-BRED INTERNATIONAL, INC. (US) 2024-04-16 US disclosed
US-20240018194-A1 INSECTICIDAL PROTEINS AND METHODS FOR THEIR USE PIONEER HI-BRED INTERNATIONAL, INC. (US) 2024-01-18 US disclosed
US-11780891-B2 Insecticidal proteins and methods for their use PIONEER HI-BRED INTERNATIONAL, INC. 2023-10-10 US disclosed
EP-4050021-A1 INSECTICIDAL PROTEINS AND METHODS FOR THEIR USE Pioneer Hi-Bred International, Inc. (US) 2022-08-31 EP disclosed
EP-3535285-B1 INSECTICIDAL PROTEINS AND METHODS FOR THEIR USE PIONEER HI BRED INT (US) 2022-04-06 EP disclosed