Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 6/20 | 1.00 |
| ▸ | CD74 | P04233 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 8/20 | 0.78 |
| ▸ | LMNA | P02545 | 5/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.77 |
| ▸ | HPGD | P15428 | 2/20 | 0.77 |
| ▸ | USP2 | O75604 | 1/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.75 |
| ▸ | HTT | P42858 | 5/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17167058 | 1.00 | MIF (1.00) | MIFCD74TSHRLMNAL3MBTL1 | |
| SCHEMBL18805700 | 0.89 | MIF (1.00) | MIFCD74TSHRLMNAL3MBTL1 | |
| SCHEMBL18805684 | 0.88 | TSHR (1.00) | MIFCD74TSHRLMNAL3MBTL1 | |
| SCHEMBL10089276 | 0.88 | MIF (0.78) | MIFCD74TSHRLMNAL3MBTL1 | |
| SCHEMBL29566244 | 0.86 | MIF (1.00) | MIFCD74TSHRLMNAL3MBTL1 | |
| SCHEMBL3266381 | 0.86 | MIF (1.00) | MIFCD74TSHRLMNAL3MBTL1 | |
| SCHEMBL17156117 | 0.85 | MIF (0.74) | MIFCD74TSHRLMNAL3MBTL1 | |
| SCHEMBL18805698 | 0.85 | TSHR (0.78) | MIFCD74TSHRLMNAL3MBTL1 | |
| SCHEMBL18805693 | 0.79 | MIF (0.82) | MIFCD74TSHRLMNAL3MBTL1 | |
| SCHEMBL10874258 | 0.79 | MIF (1.00) | MIFCD74TSHRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237002-A1 | METHODS OF TREATING SPONDYLOARTHRITIS OR SYMPTOMS THEREOF | University Health Network (CA) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022087719-A1 | METHODS OF TREATING SPONDYLOARTHRITIS OR SYMPTOMS THEREOF | UNIVERSITY HEALTH NETWORK (CA) | 2022-05-05 | — | — | WO | disclosed |