Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 8/20 | 1.00 |
| ▸ | CD74 | P04233 | 4/20 | 0.76 |
| ▸ | TSHR | P16473 | 6/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266381 | 1.00 | MIF (1.00) | MIFCD74TSHRL3MBTL1LMNA | |
| SCHEMBL18805693 | 0.90 | MIF (0.82) | MIFCD74TSHRL3MBTL1LMNA | |
| SCHEMBL18805683 | 0.90 | MIF (1.00) | MIFCD74TSHRL3MBTL1LMNA | |
| SCHEMBL10089276 | 0.86 | MIF (0.78) | MIFCD74TSHRL3MBTL1LMNA | |
| SCHEMBL17167058 | 0.86 | MIF (1.00) | MIFCD74TSHRL3MBTL1LMNA | |
| SCHEMBL29565887 | 0.86 | MIF (1.00) | MIFCD74TSHRL3MBTL1LMNA | |
| SCHEMBL2757854 | 0.82 | MIF (0.70) | MIFCD74TSHRL3MBTL1LMNA | |
| SCHEMBL16554239 | 0.78 | MIF (0.70) | MIFCD74MAPT | |
| SCHEMBL29566638 | 0.77 | MIF (1.00) | MIFCD74 | |
| SCHEMBL18805682 | 0.77 | MIF (1.00) | MIFCD74 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237002-A1 | METHODS OF TREATING SPONDYLOARTHRITIS OR SYMPTOMS THEREOF | University Health Network (CA) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022087719-A1 | METHODS OF TREATING SPONDYLOARTHRITIS OR SYMPTOMS THEREOF | UNIVERSITY HEALTH NETWORK (CA) | 2022-05-05 | — | — | WO | disclosed |