⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL522616 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28198127 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL6986442 | 0.98 | — | — | |
| Iodide SCHEMBL29069910 | 0.98 | — | — | |
| Acetic Acid SCHEMBL28084604 | 0.88 | — | — | |
| Propionic Acid SCHEMBL28130761 | 0.87 | FFAR3 (0.36) | — | |
| Trifluoromethanesulfonic Acid SCHEMBL28351575 | 0.81 | — | — | |
| Levulinic Acid SCHEMBL28963776 | 0.80 | LMNA (0.42) | — | |
| SCHEMBL11762677 | 0.79 | — | — | |
| SCHEMBL9435750 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307400-A | Preparation method of S-flurbiprofen | 金仓(上海)医药生物科技有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-118064400-B | S-selective omega-aminotransferase mutant with high catalytic activity, and construction method and application thereof | 中国科学院苏州生物医学工程技术研究所 | 2024-06-25 | — | — | CN | claimed |
| CN-118239904-A | Chiral synthesis method of 2, 6-diamino-4, 5,6, 7-tetrahydrobenzothiazole optical isomer | 福建福瑞明德药业有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118064400-A | S-selective omega-aminotransferase mutant with high catalytic activity, and construction method and application thereof | 中国科学院苏州生物医学工程技术研究所 | 2024-05-24 | — | — | CN | claimed |
| CN-114787171-B | Industrial preparation method of compound | 智腾大中华区有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-117677605-A | Process for preparing levetiracetam and intermediates thereof | 维生源知识产权有限责任公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117587078-A | Preparation method of apremilast drug intermediate | 华中科技大学 | 2024-02-23 | — | — | CN | claimed |
| CN-117230129-A | Method for preparing chiral arylamine compound by using aminotransferase or mutant thereof | 上海合全药业股份有限公司 | 2023-12-15 | — | — | CN | claimed |
| CN-116555364-A | Preparation method of aminocyclohexyl compound | 上海合全药业股份有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-116555366-A | Method for preparing chiral lactam compound by using aminotransferase mutant | 上海合全药物研发有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-105903457-A | Imidazole ionic liquid chiral stationary phase and preparation method and application | 中国科学院青岛生物能源与过程研究所 | 2016-08-31 | — | — | CN | claimed |
| EP-2735560-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 2-METHYLPROLINE DERIVATIVE | Kaneka Corporation (JP) | 2014-05-28 | — | — | EP | claimed |
| US-20140142336-A1 | SYNTHETIC METHOD OF ENANTIOMERICALLY PURE 2,2'-DIHYDROXY-1,1'-BINAPHTHYL-3-CARBOXYLIC ACID | AMINOLOGICS CO., LTD. (KR) | 2014-05-22 | — | — | US | claimed |
| EP-2643284-A2 | SYNTHETIC METHOD OF ENANTIOMERICALLY PURE 2,2'-DIHYDROXY-1,1'-BINAPHTHYL-3-CARBOXYLIC ACID | Aminologics Co., Ltd (KR) | 2013-10-02 | — | — | EP | claimed |
| US-20130210092-A1 | Novel Transaminase, Gene Encoding the Same, and Method Using Them | KANEKA CORPORATION (JP) | 2013-08-15 | — | — | US | claimed |
| EP-2623595-A1 | NOVEL TRANSAMINASE SHOWING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR UTILIZATION THEREOF | Kaneka Corporation (JP) | 2013-08-07 | — | — | EP | claimed |
| EP-2623593-A1 | NOVEL AMINOTRANSFERASE AND GENE ENCODING SAME, AND USE OF THE AMINOTRANSFERASE AND THE GENE | Kaneka Corporation (JP) | 2013-08-07 | — | — | EP | claimed |
| US-20130196389-A1 | NOVEL TRANSAMINASE EXHIBITING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR USING THEM | KANEKA CORPORATION (JP) | 2013-08-01 | — | — | US | claimed |
| CN-101500691-B | Method for separating co2 from gas mixtures | UNIV DORTMUND | 2011-09-28 | — | — | CN | claimed |
| CN-101500691-A | Method for separating co2 from gas mixtures | UNIV DORTMUND (DE) | 2009-08-05 | — | — | CN | claimed |